Mary A Ndiaye Selected Research

BI 6727

2/2022	PLK1 inhibition-based combination therapies for cancer management.
1/2021	PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways.
1/2017	Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo.

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Mary A Ndiaye Research Topics

Disease

14	Neoplasms (Cancer) 02/2022 - 03/2007
5	Melanoma (Melanoma, Malignant) 01/2022 - 01/2014
4	Carcinogenesis 08/2020 - 01/2019
2	Body Weight (Weight, Body) 01/2022 - 01/2017
2	Prostatic Neoplasms (Prostate Cancer) 08/2020 - 06/2014
2	medullary Thyroid cancer 03/2007 - 12/2006
1	Neoplasm Metastasis (Metastasis) 01/2022
1	Adenocarcinoma 08/2020
1	Acute-Phase Reaction 10/2019
1	Skin Neoplasms (Skin Cancer) 01/2019
1	Nevus (Nevi) 01/2017

Drug/Important Bio-Agent (IBA)

3	BI 6727IBA 02/2022 - 01/2017
3	Sirtuin 1IBA 01/2022 - 01/2014
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2018
3	AntioxidantsIBA 08/2020 - 06/2015
3	PowdersIBA 07/2020 - 01/2019
2	Phosphotransferases (Kinase)IBA 02/2022 - 01/2021
2	Polo-Like Kinase 1IBA 01/2021 - 01/2017
2	ResveratrolIBA 08/2020 - 06/2015
2	Transcription Factors (Transcription Factor)IBA 08/2020 - 12/2006
2	SirtuinsIBA 01/2018 - 01/2014
1	BI 2536IBA 02/2022
1	onvansertibIBA 02/2022
1	afimoxifene (hydroxytamoxifen)IBA 01/2022
1	ChemokinesIBA 01/2022
1	5- (2- (4- bromophenyl)vinyl)- 1,3- benzenediolIBA 01/2022
1	Sirtuin 3IBA 01/2022
1	CytokinesIBA 01/2022
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	3- (4- ((4- chlorophenyl)sulfonyl)- 4- (2,5- difluorophenyl)cyclohexyl)propanoic acidIBA 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	AndrogensIBA 08/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 08/2020
1	QuercetinIBA 08/2020
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 07/2020
1	Immunoglobulin E (IgE)IBA 07/2020
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 10/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019
1	Sunscreening Agents (Sunscreens)IBA 01/2019
1	Sirtuin 2IBA 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	liquid crystal polymerIBA 01/2017
1	Caspase 3 (Caspase-3)IBA 01/2017
1	Selenomethionine (Sethotope)FDA Link 06/2014
1	Vitamin E FDA LinkGeneric 06/2014
1	alpha-Tocopherol FDA Link 06/2014
1	Tocopherols (Tocopherol)IBA 06/2014
1	methylselenic acidIBA 06/2014
1	SeleniumIBA 06/2014
1	sirtinolIBA 01/2014
1	tenovin-1IBA 01/2014
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2014
1	6- chloro- 2,3,4,9- tetrahydro- 1H- carbazole- 1- carboxamideIBA 01/2014
1	Glycogen Synthase Kinase 3 betaIBA 03/2007
1	Glycogen Synthase (Synthase I)IBA 03/2007
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 03/2007
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 12/2006
1	Chromogranin AIBA 12/2006

Therapy/Procedure

3	Therapeutics 02/2022 - 01/2017
1	Drug Therapy (Chemotherapy) 02/2022
1	Chemoprevention 10/2019
1	Intravenous Injections 01/2017